Immunoblastic lymphadenopathy with centrofollicular PAS-positive inclusions.

The authors describe the clinical and histopathologic picture of immunoblastic lymphadenomegaly in a 66-year-old patient with allergic antecedents. The condition of the patient ameliorated following cortisone and antibiotic therapy, but adenomegalia relapsed after several months. PAS-positive granular inclusions were found in the macrophage cells in the germinative centres of the follicles, showing the aspect of a blockade with nuclear significance.

Antimyocardial antibodies in heart diseases. II. Immunofluorescent patterns in rheumatic fever and rheumatic heart disease.

Antibodies against rat myocardium were studied by means of histoimmunfluorescence (indirect technique) in 32 rheumatic fever patients. Antibodies were found in 54% of the cases without carditis or active rheumatic valvulitis and in 83% of those with carditis. The fluorescent patterns observed were : sarcolemmal, sarcoplasmic (intermyofibrillar) and smooth muscle of vessels.