Gut resident profile predicts the eighteen-month probability and antimicrobial susceptibility of urinary tract infections.

Background: Community-acquired UTI is the most common bacterial infection managed in general medical practice that can lead to life-threatening outcomes. While UTIs are primarily caused by colonizing the patient's gut, it is unclear whether the gut resident profiles can predict the person's risks for UTI and optimal antimicrobial treatments. Thus, we conducted an eighteen-month long community-based observational study of fecal colonization and UTI in women aged 50 years and above.

Increase in the Rate of Gut Carriage of Fluoroquinolone-Resistant Escherichia coli despite a Reduction in Antibiotic Prescriptions.

Fluoroquinolone use for urinary tract infections has been steadily declining. Gut microbiota is the main reservoir for uropathogenic but whether the carriage of fluoroquinolone-resistant has been changing is unknown. .

[CATALITICAL PROPERTIES OF LIVER MONOAMINE OXIDASE IN THE CHUM SALMON ONCORHYNCHUS KETA].

The substrate and inhibitory specificity of mitochondrial monoamine oxidase (MAO) in the liver of males of the summer form of the chum salmon Oncorhynchus keta was studied. As to the spectrum of deaminated substrates, the hepatic MAO of the chum salmon is similar to MAO of most terrestrial mammals, for eight classical MAO substrates similarity in their substrate characteristics were found. Analysis of the antimonoamine oxidase activity of two derivaties of 2-propinilamine, five derivatives of acridine as well as of pyronine G revealed significant qualitative and quantitative differences as compared to the hepatic enzyme of tuna and whitefish.

[Enzymological characteristics of liver monoamine oxidase of the skipjack tuna Katsuwonus pelamis].

There has been carried out a study of substrate and inhibitor specificity of the liver mitochondrial monoamine oxidase (MAO) of the striped-bellied tunny Katsuwonus pelamis. Results of the substrate-inhibitor analysis with use of chlorgilin and deprenyl are an indirect proof for the existence in the tunny liver of one molecular MAO form. The studied enzyme, like the liver MAO of terrestrial mammals, deaminates tyramine, tryptamine, dopamine, serotonin, noradrenalin, benzylamine, β-phenylethylamine, and N-methylhistamine, does not deaminate histamine and is not inhibited by 10 mM semicarbaside.