[Miniature thin layer biosensors which are sensitive to glutamate and glutamine].

Integrated thin film biosensors for simultaneous measurement of L-glutamine and L-glutamate in a micro-flow cell were developed. Due to a novel glutaminase with an activity optimum in the neutral pH range a direct monitoring of glutamine in mammalian cell culture medium could be performed. The glutamine bienzyme sensor was prepared by coimmobilization of glutaminase with glutamate oxidase within a photo patterned poly(2-hydroxyethyl methacrylate) (pHEMA) hydrogel membrane.

[Plica polonica].

The author summarizes the essentials and history of the plica polonica disease and describes some of his own experiences in diagnosis and treatment. It is remarkable, that the monographs of the internal medicine and the hungarian monographs of dermatology, with the exception of two, didn't even mention this phenomenon in this century. Besides, no original publications can be found in the hungarian medical literature about this topic.