Publications by authors named "I Morales"
Background And Objectives: Multiple sclerosis (MS) affects more than 1 million people in the United States, including reproductive-age women. There has been a paucity of prospective, pregnancy registries based on MS disease rather than medication exposures. A prospective MS pregnancy registry (PREG-MS) was established in 2017 as a prospective, single-cohort, real-world MS pregnancy registry in New England States of the United States, with goals to evaluate (1) course of MS and disease-modifying therapies (DMT) use during conception attempts and in the peripartum period, (2) pregnancy outcomes in women with MS (WwMS), and (3) longer-term developmental outcomes in offspring of WwMS.
View Article and Find Full Text PDFBackground: Pseudomonas aeruginosa (PA) bloodstream infection (BSI) is a common healthcare-associated complication linked to antimicrobial resistance and high mortality. Ongoing clinical trials are exploring novel anti-virulence agents, yet studies on how bacterial virulence affects PA infection outcomes is conflicting and data from real-world clinical populations is limited.
Methods: We studied a multicentre cohort of 773 adult patients with PA BSI consecutively collected during 7-years from sites in Europe and Australia.
Article Synopsis
- * Researchers are exploring "smart" composites that can change their characteristics in response to external triggers, such as becoming softer for easier excision of implants.
- * This study demonstrates the use of functional organosilica nanoparticles that respond to alternating magnetic fields, generating heat and enabling quick detachment from the polymer matrix through a retro-Diels-Alder reaction.
Article Synopsis
- The increasing population in Yucatan is driving construction in the Mayan jungle for tourism, housing, and agriculture, alongside a rise in rabies cases in cats.
- A study was conducted to analyze rabies viruses in felines through genetic and antigenic characterization, using ArcGIS and R software for mapping case locations.
- Nine rabies cases from 2003-2022 were identified, revealing three antigenic variants predominantly linked to urban areas, emphasizing the risk of reintroducing rabies in dogs if vaccination rates decline.