Bilateral Inflammatory Optic Neuropathy Related to Graft versus Host Disease Following Allogeneic Bone Marrow Transplantation for Hodgkin Disease.

Graft versus host disease (GvHD) is a common and often troublesome complication of allogeneic bone marrow transplantation. Neurological complications usually involve the peripheral nervous system and muscle, but the central nervous system may be affected. When an optic neuropathy develops, it is often difficult to determine the cause quickly; infective complications and drug toxicity may have arisen, but an inflammatory disorder due to GvHD should also be considered, particularly since treatment with steroids and immune suppression may improve the outcome significantly.

Is dry eye associated with acquired aponeurogenic blepharoptosis?

Purpose: To study the relation between signs of dry eye and acquired aponeurogenic blepharoptosis.

Methods: Prospective case-control study in which 100 patients with uni-or bilateral acquired aponeurogenic blepharoptosis were matched for age and gender to 100 controls. The margin-reflex distance (MRD), the Schirmer-1 score, the duration of the tear film break up time (BUT), and the presence of any corneal staining with fluorescein were evaluated in both groups and compared.

Nitrous oxide cryotherapy for primary periocular basal cell carcinoma: outcome at 5 years follow-up.

Aim: To report the outcome at 5-year follow-up of a defined series of patients with primary periocular basal cell carcinoma treated by cryotherapy using a nitrous oxide probe.

Methods: A prospective, non-comparative, interventional case series. One hundred primary periocular basal cell carcinomas were treated with a double freeze-thaw cycle nitrous oxide contact cryotherapy probe.

Corneal graft dehiscence during swinging eyelid orbital decompression.

A 68-year-old man with Graves orbitopathy underwent a bilateral swinging eyelid orbital decompression for disfiguring proptosis. A penetrating keratoplasty for keratoconus of the left eye had been performed 13 years earlier. Prior to orbital decompression, biomicroscopy of the left eye showed a partially decompensated sutureless corneal graft with good wound apposition.

[Waldenstrom's macroglobulinaemia of the lacrimal gland in a patient with sarcoidosis].

We report a case of bilateral lacrimal gland involvement as the first sign of Waldenstrom's macroglobulinaemia in a patient with sarcoidosis. Histological analysis of an incisional biopsy revealed a lymphoplasmocytic lymphoma consistent with Waldenstrom's macroglobulinaemia. No noncaseating granulomas were encountered.