[The ethnic factor in dentistry as a component of personalized medicine].

Personalized medicine is the choice of treatment based on the individual characteristics of the patient due to genetic and environmental factors. The latter are to a certain degree determined by an ethnic group. This article discusses ethnic aspects in the structure of the maxillofacial area, the prevalence, development, treatment and prevention of dental diseases.

Antiproliferative, cytotoxic, antioxidant activity and polyphenols contents in leaves of four Staphylea L. species.

Staphylea has been used for long time in Traditional Chinese Medicine (TCM) and by Native Americans in a number of therapeutical indications. The present study describes in vitro antiproliferative, cytotoxic properties (MTT and LDH test) and antioxidant activities (reduction of DPPH radical and peroxynitrite radical) of Staphylea colchica Stev. (SC), S.

Anti-inflammatory potential and fatty acid content of lipophilic leaf extracts of four Staphylea L. species.

Staphylea preparations are used in TCM and have been used by native Americans for a number of indications, such as rheumatism. Based on this knowledge, the anti-inflammatory activity of light petroleum extracts of leaves of Staphylea colchica Stev., S.

Antioxidant activity and total phenols in different extracts of four Staphylea L. Species.

Staphylea L. is a deciduous ornamental shrub that possesses significant cytotoxic and antibacterial activity, although the chemical composition of its extracts and the identity of the structures responsible for these biological activities are not yet known. In this study we have determined the total phenolic content in chloroform and ethyl acetate extracts of four Staphylea species: Staphylea colchica Stev.

Antiprotease and antimetastatic activity of ursolic acid isolated from Salvia officinalis.

Proteases play a regulatory role in a variety of pathologies including cancer, pancreatitis, thromboembolic disorders, viral infections and many others. One of the possible strategies how to combat with these pathologies seems to be the use of low molecular inhibitors. Natural products were evaluated in the in vitro antiprotease assay on serine proteases (trypsin, thrombin and urokinase) and on the cysteine protease cathepsin B.