Publications by authors named "I Marjanovic"
This study analyzed 2102 conjunctival lesions excised between 1981 and 2003 at a single tertiary center in Serbia, with the aim of evaluating their histopathological characteristics, anatomical localization, and demographic distribution. Of the total cases recorded, 55.1% were male, indicating a slight male predominance.
View Article and Find Full Text PDFBackground: Cytarabine-anthracycline-based induction chemotherapy remains the standard of care for remission induction among patients with newly diagnosed acute myeloid leukaemia (AML). There are remarkable differences in therapy response among AML patients. This fact could be partly explained by the patients' genetic variability related to the metabolic paths of cytarabine and anthracyclines.
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- A study examined gender differences in dry eye symptoms after surgery for eyelid conditions in 109 patients aged 65-89.
- Men initially had lower tear stability but higher tear production compared to women; however, these differences became less pronounced over time.
- Women reported more severe dry eye symptoms both before and after surgery, indicating a need for gender-sensitive approaches in postoperative care.
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- The study explored the use of next-generation sequencing (NGS) to identify genetic variants in 55 children with childhood epilepsy of unknown origins, ultimately diagnosing about 50.9% of the cases.* -
- Researchers found variants in 22 different epilepsy-associated genes, with significant findings related to SCN1A, ALDH7A1, and KCNQ2, which could inform targeted therapies for some patients.* -
- The discovery of novel genetic variants enhances the understanding of the genetic factors linked to childhood epilepsy and aims to improve diagnosis and treatment strategies globally.*
Telomerase Reverse Transcriptase (TERT) encodes the telomerase reverse transcriptase enzyme and is the most frequently mutated gene in patients with telomeropathies. Heterozygous variants impair telomerase activity by haploinsufficiency and pathogenic variants are associated with bone marrow failure syndrome and predisposition to acute myeloid leukaemia. Owing to their rarity, telomeropathies are often unrecognised and misdiagnosed.
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