Publications by authors named "I MOLOCZNIK"
We report on a series of 48 patients, ages 14 to 20 year, with hypophyseal adenomas. Of these, 46 (96%) had secreting tumors, 3 had Cushing's disease, 9 had somatotrophinomas, and 34 (29 females and 5 males) had prolactinomas. Thirty cases were diagnosed as intrasellar adenomas (62%) while the remaining eighteen (38%) presented extrasellar expansion.
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- * In comparison to placebo, bromocriptine caused a 70% reduction in prolactin levels in both groups, and a significant decrease in norepinephrine levels only in the control group.
- * Results indicated that bromocriptine may not be effective for diagnosing issues with central dopaminergic regulation due to varying individual responses in tumor patients, though the overall impaired response suggests a possible issue with dopamine receptor activity in these patients.