Delineation of the Genetic Architecture and Clinical Polymorphism of 3q29 Duplication Syndrome: A Review of the Literature and a Report of Two Novel Patients With Single-Gene BDH1 Duplications.

Background: Chromosome 3q29 duplication syndrome is a rare chromosomal disorder with a frequency of 1:5000 in patients with a neurodevelopmental phenotype. The syndrome is characterized by phenotypic polymorphism and reduced penetrance.

Methods: Patients were investigated by performing a cytogenetic analysis of GTG-banded metaphases, aCGH with the SurePrint G3 Human CGH Microarray 8×60K, qPCR, FISH, and WES.

The Synthesis of Materials with a Hierarchical Structure Based on Tin Dioxide.

This article presents the results of the formation of hierarchical micro-nano structures in nanostructured tin dioxide films obtained from the lyophilic film-forming system SnCl/EtOH/NHOH. The classification of the shape and size of the synthesized structures, in relation to the pH of the solution, is presented. Measurements were carried out on an X-ray diffractometer to study the crystal structure of the samples analyzed.

ANALYSIS OF BLOOD PARAMETERS IN TYUMEN RESIDENTS WITH COVID-19 IN CATAMNESIS AND/OR VACCINATED AGAINST A NEW CORONAVIRUS INFECTION.

Currently, much is known about the causative agent of Covid-19. The situation with the spread of a new coronavirus infection is under control. Preventive measures against this disease have been developed and are being actively implemented.

[Progressive multifocal leukoencephalopathy in HIV-positive individuals].

The article discusses the historical aspect and modern ideas about the etiology and pathogenesis of progressive multifocal leukoencephalopathy in patients with HIV infection. An analysis and synthesis of literature data on the clinical presentation of this pathology was carried out. The possibilities and limitations of laboratory and instrumental diagnostic methods, including neuroimaging methods, are discussed in detail.