Publications by authors named "I M Larsson"

Introduction: Knee pain increases the risk of developing chronic widespread pain (CWP) and knee osteoarthritis (KOA). The prevalence of CWP and KOA has increased, and there is a need for early prevention. Therefore, the aim was to examine the associations of health-related quality of life (HRQoL) and lifestyle habits with chronic pain at a two-year follow-up in individuals with knee pain.

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Background: Healthy lifestyle habits (regular physical activity, a healthy diet, no smoking and non-hazardous alcohol consumption) alongside pharmacological treatment can lower the risk of cardiovascular diseases and improve symptoms and quality of life in patients with rheumatoid arthritis (RA). Therefore, healthcare professionals in rheumatology care are urged to discuss lifestyle habits with all patients. The aim of this study was to explore patients' perceptions of lifestyle discussions in early rheumatology care.

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Background: It has been suggested that the university environment, to improve students' health status and educational outcomes, should be based on a health promoting approach. More knowledge is needed about health promoting resources and lifestyle factors that may be of value for students in higher education and their future work-life balance. The aim of this study was to explore health-promoting resources, general health and wellbeing, and health promoting lifestyle factors among fourth and final semester students in higher education in healthcare and social work.

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Article Synopsis
  • Nervous system cancers show different cell states influenced by various factors, but understanding their regulation and potential treatments is still lacking.
  • The "single-cell regulatory-driven clustering" (scregclust) method analyzes single-cell RNA sequencing data to identify key regulatory programs in brain tumors and developing tissues, efficiently predicting important transcription factors and kinases.
  • Using this method, critical regulators were found that might enhance temozolomide treatment for glioblastoma, and its flexibility was proven by applying it to different tumor types, making it accessible as a user-friendly R package for further research.
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  • The study investigated how self-reported eating behaviors impact weight changes over 24 months in adults with severe obesity, involving 971 participants (75% women) with a mean BMI of 42.0 kg/m².
  • The results showed that those who engaged in nocturnal eating lost less weight compared to those who did not, while binge eating disorder did not significantly affect weight loss over this period.
  • Emotional eating was linked to less weight loss at 12 months and was a factor in participants dropping out of medical treatment, highlighting the importance of addressing harmful eating behaviors in obesity treatment.
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