[Plasminogen activation by antiplasminogen monoclonal antibody IV-1C. Properties and mechanism of reaction].

In review the results of investigation of plasminogen(Pg) activation by antiplasminogen monoclonal antibody IV-1c have been presented. Antigenic determinant of IV-1c was localized in Val709-Gly718 site of Pg protease domain. IV-1c completely inhibited the Pg activation by streptokinase, but increased the rate of Pg activation by t-PA and urokinase.

Specific identification of Mycobacterium bovis by monoclonal antibody-based enzyme immunoassay.

To improve identification of M. bovis, rabbit immune sera and mouse monoclonal antibodies against M. bovis-secreted protein antigens were used in the enzyme-linked assay (ELISA).