Publications by authors named "I M Kolesnikova"
Obesity is associated with changes in the gut microbiota, as well as with increased permeability of the intestinal wall. In 130 non-obese volunteers, 57 patients with metabolically healthy obesity (MHO), and 76 patients with metabolically unhealthy obesity (MUHO), bacterial DNA was isolated from stool samples, and the 16S rRNA gene was sequenced. The metabolic profile of the microbiota predicted by PICRUSt2 (https://huttenhower.
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- Inflammatory bowel diseases involve ongoing inflammation in the intestines and changes in gut microbiota, which can be influenced by outer membrane vesicles (OMVs) that contain polysaccharide A (PSA).
- The study used a mouse model of intestinal colitis induced by sodium dextran sulfate (DSS) and examined the effects of OMV treatment by assessing disease severity and gut tissue health through disease activity index (DAI) and histology.
- Results indicated that OMV treatment improved intestinal healing and altered microbiota composition, highlighting OMVs’ potential as both anti-inflammatory agents and facilitators of microbiota recovery.
Background: Children have a right to participate in decisions about their lives. They also have the right to family and cultural connection, including when they are removed due to child protection concerns. However, the literature highlights barriers children in out-of-home care experience connecting to family-of-origin and culture.
View Article and Find Full Text PDFCurrently, obesity is a critical global public health burden. Numerous studies have demonstrated the regulation of the pathogenesis of obesity and metabolic abnormalities by the gut microbiota and microbial factors; however, their involvement in the various degrees of obesity is not yet well understood. Previously, obesity has been shown to be associated with decreased levels of vitamin B12.
View Article and Find Full Text PDFBackground: Rising global concerns about COVID-19 recently gained more research attention due to the ease of person-to-person transmission, various symptoms after healing, and the shortage of effective antiviral therapy. The study aims to analyze post-COVID conditions and clinical manifestations of cardiovascular lesions in patients recovering from COVID-19 infection.
Methods: A practical examination of post-COVID conditions manifestation was conducted in a prospective cohort study, involving 250 patients diagnosed with COVID-19 between June 1, 2021, and August 31, 2021.