Publications by authors named "I M Kantola"
Article Synopsis
- A study analyzed data from 83 patients with Fabry disease who switched from agalsidase beta to migalastat, focusing on their kidney function, protein levels in urine, and other heart-related measurements.
- Results showed that kidney function (eGFR) declined more sharply after the switch, with significant differences between classic and late-onset patients.
- The study highlights variability in patient outcomes post-switch, suggesting the need for ongoing monitoring to manage their health effectively.
Enhanced rock weathering (EW) is an emerging atmospheric carbon dioxide removal (CDR) strategy being scaled up by the commercial sector. Here, we combine multiomics analyses of belowground microbiomes, laboratory-based dissolution studies, and incubation investigations of soils from field EW trials to build the case for manipulating iron chelators in soil to increase EW efficiency and lower costs. Microbial siderophores are high-affinity, highly selective iron (Fe) chelators that enhance the uptake of Fe from soil minerals into cells.
View Article and Find Full Text PDFObjective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 2023. The questionnaire contained 64 questions asking ESH-ECs representatives to estimate how patients with CKD are managed.
View Article and Find Full Text PDFArticle Synopsis
- - A 2023 survey by the European Society of Hypertension assessed the management of chronic kidney disease (CKD) patients with hypertension across 88 centers in 27 countries, finding that only 28% had preexisting CKD, and 30% exhibited resistant hypertension.
- - The survey indicated inconsistent rates of recent kidney function tests and varying usage of important medications, showing higher rates of certain drugs when nephrologists were involved in the care team.
- - Overall, the study highlighted significant gaps in CKD screening and treatment prior to referral for specialized care, suggesting that tailored initiatives could enhance management for patients with hypertension and CKD.
Results from two independent clinical validation studies for measuring hemodynamics at the patient's bedside using a compact finger probe are reported. Technology comprises a barometric pressure sensor, and in one implementation, additionally, an optical sensor for photoplethysmography (PPG) is developed, which can be used to measure blood pressure and analyze rhythm, including the continuous detection of atrial fibrillation. The capabilities of the technology are shown in several form factors, including a miniaturized version resembling a common pulse oximeter to which the technology could be integrated in.
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