Publications by authors named "I M KHEINONEN"

Clinical investigation of 31 patients with idiopathic hypertrophic subaortal stenosis (IHSS) and idiopathic hypertrophic nonobstructive cardiomyopathy (IHNCMP) comprised electro- and phonocardiography, roentgenologic examination and echocardiography. The disease was latent in 3 patients, and ischemic heart disease or rheumatic heart lesion had been diagnosed prior to echocardiography in 26. Asymmetrical hypertrophy and hypokinesia of the upper third of the ventricular septum, narrowed left-ventricular cavity and septum-wise systolic movement of the anterior mitral cusp were findings common to all IHSS patients.

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Correlations between clinical pattern of the disease, electrocardiographic evidence of necrosis from standard leads and the size of infarction expressed in CPK gram-equivalents were examined in 92 patients with acute primary transmural myocardial infarction. In addition, maximum total CPK activity and the pattern of the curve obtained through serial measurements were assessed. The patients were divided in five groups depending on electrocardiographic evidence of necrotic spread, which differed significantly in terms of both enzyme activity and clinical pattern of the disease.

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