Publications by authors named "I M J Saris"
Article Synopsis
- Social dysfunction is a common feature of neuropsychiatric disorders like Schizophrenia and Alzheimer's disease, impacting socioaffective neural processing.
- A study analyzed how social dysfunction correlates with brain system activity in SZ and AD patients through fMRI tasks, revealing patterns related to emotional responses.
- The research found that severe behavioral social dysfunction linked to hyperactivity and hypoactivity in specific brain regions, highlighting the potential for tailored care based on individual social behavior.
Theory of Mind and social functioning among neuropsychiatric disorders: A transdiagnostic study.
Eur Neuropsychopharmacol
November 2022
Social dysfunction is commonly present in neuropsychiatric disorders of schizophrenia (SZ) and Alzheimer's disease (AD). Theory of Mind (ToM) deficits have been linked to social dysfunction in disease-specific studies. Nevertheless, it remains unclear how ToM is related to social functioning across these disorders, and which factors contribute to this relationship.
View Article and Find Full Text PDFBackground: Social functioning is often impaired in schizophrenia (SZ) and Alzheimer's disease (AD). However, commonalities and differences in social dysfunction among these patient groups remain elusive.
Materials And Methods: Using data from the PRISM study, behavioral (all subscales and total score of the Social Functioning Scale) and affective (perceived social disability and loneliness) indicators of social functioning were measured in patients with SZ (N = 56), probable AD (N = 50) and age-matched healthy controls groups (HC, N = 29 and N = 28).
Relationships between social withdrawal and facial emotion recognition in neuropsychiatric disorders.
Prog Neuropsychopharmacol Biol Psychiatry
March 2022
Background: Emotion recognition constitutes a pivotal process of social cognition. It involves decoding social cues (e.g.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the link between social dysfunction and the Default Mode Network (DMN), which is important in neuropsychiatric disorders, focusing on patients with schizophrenia and Alzheimer’s alongside healthy controls.
- Using fMRI data, the research found that measures of social dysfunction (via specific scales) were associated with reduced DMN connectivity, particularly in certain brain regions.
- The results suggest that changes in DMN connectivity could serve as potential biomarkers for social dysfunction across various mental health disorders, which may help in developing personalized treatment strategies.