Publications by authors named "I M Graf"
Terrestrial enhanced rock weathering (ERW) is a promising carbon dioxide removal technology that consists in applying ground silicate rock such as basalt on agricultural soils. On top of carbon sequestration, ERW has the potential to raise the soil pH and release nutrients, thereby improving soil fertility. Despite these possible co-benefits, concerns such as heavy metal pollution or soil structure damage have also been raised.
View Article and Find Full Text PDFArticle Synopsis
- Microglia play a key role in post-stroke inflammation, impacting neurological recovery.
- The study examines how lipid droplet (LD) buildup in microglia under stroke conditions leads to pro-inflammatory responses and worsens brain damage.
- Findings reveal that LD-rich microglia (LDRM) exhibit increased inflammatory markers and distinct lipid profiles, highlighting their contribution to worsened outcomes in neuroinflammatory conditions.
Article Synopsis
- Gingivitis is prevalent in young patients with chronic kidney disease (CKD) and managing it requires a collaborative approach; this study compared the effects of a more intensive oral care program versus standard preventive measures on the tongue microbiome of CKD patients.
- The study involved 30 participants with CKD and gingivitis, analyzing tongue samples over six months to assess microbial changes using advanced genetic sequencing techniques.
- Results indicated that neither intervention significantly altered the microbiome composition, demonstrating the stability and resilience of the tongue microbiome in children with CKD, even with improved oral hygiene.
Sound produces surface waves along the cochlea's basilar membrane. To achieve the ear's astonishing frequency resolution and sensitivity to faint sounds, dissipation in the cochlea must be canceled via active processes in hair cells, effectively bringing the cochlea to the edge of instability. But how can the cochlea be globally tuned to the edge of instability with only local feedback? To address this question, we use a discretized version of a standard model of basilar membrane dynamics, but with an explicit contribution from active processes in hair cells.
View Article and Find Full Text PDFArticle Synopsis
- Sound waves create surface waves on the cochlea's basilar membrane, and to maximize hearing sensitivity and frequency resolution, active processes in hair cells help maintain stability.
- The study uses a model of the basilar membrane that includes these active processes, revealing two types of modes: localized modes that can be amplified independently, and collective extended modes that are sensitive to destabilization.
- The research highlights how individual hair cells work together to maintain a delicate balance, or 'critical cochlea,' which is essential for optimal hearing performance.