EEG discriminant analyses of mild head trauma.

Measures of EEG power spectral analyses were obtained from a total of 608 mild head trauma patients and 108 age-matched normal subjects. A training-set discriminant function was first developed from 264 mild head-injured patients and 83 age-matched controls yielding an overall discriminant classification accuracy of 94.8%.

Myelin basic protein, oligoclonal bands, and IgG in cerebrospinal fluid as indicators of multiple sclerosis.

There currently are three clinical laboratory procedures for use with cerebrospinal fluid that assist in the diagnosis of multiple sclerosis: measurement of myelin basic protein and IgG, and demonstration of an oligoclonal band. We compared characteristics of these procedures, using CSF samples from 166 patients identified as having (54 patients) or not having (112 patients) multiple sclerosis. We find that oligoclonal band demonstration is the most useful single test in helping to establish the presence of multiple sclerosis; IgG quantitation is the least helpful.

Two agarose electrophoretic systems for demonstration of oligoclonal bands in cerebrospinal fluid compared.

Demonstration of oligoclonal bands by electrophoresis of cerebrospinal fluid is an important aid in establishing the diagnosis of multiple sclerosis. Electrophoretic systems vary in their effectiveness in doing so. We compared two systems in this respect.

The use of the electroencephalogram in patients admitted for alcohol abuse with seizures.

This study of 174 seizure presenting alcohol abusers revealed that the EEG is overwhelmingly normal by visual inspection. When the EEG is abnormal, however, usefulness is significant. The probable EEG findings in this group are presented and discussed here both clinically and experimentally.