Publications by authors named "I M Franklin"

Introduction: Colorectal cancer (CRC) is the second leading cause of cancer death in the United States. While patient-reported barriers have been previously described, few studies have analyzed how patients' social needs affect screening rates.

Methods: This cross-sectional study includes 3,443 Kaiser Permanente (KP) patients ages 50 to 75 years who completed the 2020 KP National Social Needs Survey.

View Article and Find Full Text PDF

Objective: At our large, university-affiliated primary care clinic, we aimed to enhance the quality of well-child checkups (WCCs) to align with Bright Futures/American Academy of Pediatrics recommendations. Our primary goal was to increase the rate of complete WCCs from 45.6% to 80% by April 2024.

View Article and Find Full Text PDF

Introduction: To examine if patients exposed to primary care telemedicine (telephone or video) early in the COVID-19 pandemic had higher rates of downstream HbA measurement and improved HbA levels in the second year of the pandemic.

Research Design And Methods: In a cohort of 242, 848 Kaiser Permanente Northern California patients with diabetes, we examined associations between early-pandemic patient-initiated telemedicine visit and downstream HbA monitoring and results during the second year of the pandemic.

Results: Adjusted HbA measurement rates were significantly higher among patients with telemedicine exposure in the early-pandemic prior year than those with no visits in the prior year (91.

View Article and Find Full Text PDF
Article Synopsis
  • Pathogenic mitochondrial DNA (mtDNA) variants are a frequent cause of mitochondrial diseases in adults, and their levels in blood decrease with age due to different metabolic needs among blood cell types.* -
  • A study involving cell-sorting and mtDNA sequencing found that T cells show a greater decline in these variants compared to other blood cells, driven by their ability to eliminate mutated mtDNA as they differentiate.* -
  • Compared to healthy controls, patients with these mtDNA variants have fewer T cells, highlighting the importance of mitochondrial function for maintaining T cell levels and differentiation status in the blood.*
View Article and Find Full Text PDF

Here we describe a combination of neodymium:yttrium-aluminium-garnet 1064-nm laser emission and injection of 75% dextrose solution to treat lower limb reticular veins. The strategy is known as cryo-laser cryo-sclerotherapy. Preliminary outcomes are reported, showing ecchymosis in up to 30% of cases and intravenous thrombus in 14%.

View Article and Find Full Text PDF