Publications by authors named "I M De Luca"
Prevalence and impact of multidrug resistance in a cohort of patients admitted to emergency department for urinary tract-infections: The UTILY study, a prospective multicentre study.
Eur J Intern Med
December 2024
Background And Aim: The aim of the present study was to evaluate the prevalence and to identify the independent predictors of multi-drug resistance among a cohort of patients admitted to emergency department for urinary tract infections (UTI), and to assess the impact of antimicrobial resistance on the clinical outcomes.
Methods: We conducted a prospective multicentre study enrolling all adult patients admitted to one of the eight emergency departments participating in the study with a microbiologically confirmed diagnosis of UTI from February 2023 to July 2024. The primary outcome evaluated was 30-day mortality; secondary outcomes included 7-day mortality and clinical response.
Objectives: To assess short-term barnidipine efficacy and tolerability on Systemic Sclerosis (SSc)-Raynaud's phenomenon (RP).
Methods: We retrospectively evaluated patients with SSc starting barnidipine 10 mg/day. Raynaud's Condition Score (RCS) and mean blood pressure (MBP) were assessed at baseline and 6-month follow-up.
Background: The best treatment for bloodstream infections (BSI) due to chromosomal AmpC (c-AmpC) producing Enterobacterales is not clearly defined.
Objectives: To describe the clinical and microbiological outcomes of patients treated with piperacillin/tazobactam, cefepime or carbapenems for bloodstream infections (BSIs) due to c-AmpC beta-lactamase-producing strains.
Data Sources: We searched MEDLINE, the Cochrane Library and EMBASE to screen original reports published up to January 2024.
Article Synopsis
- Pathogenic species of Leptospira cause leptospirosis, leading to serious infections in both animals and humans, particularly affecting major organs.
- This study analyzed kidney injury and conducted a retrospective review from dog samples at the Faculty of Veterinary Medicine in Timisoara over several years, focusing on correlation with factors like breed, gender, and infection status.
- Findings revealed a significant link between unvaccinated dogs and increased leptospirosis risk, and compared diagnostic methods, showing that qPCR was more effective and specific for detecting leptospirosis than traditional immunohistochemistry (IHC).
Periodontitis is a chronic inflammatory disease resulting from the dysbiosis of periodontal bacteria and the host's immune response, leading to tissue degradation and sustained inflammation. Traditional treatments, such as mechanical debridement and antimicrobial agents, often fail to fully eradicate pathogenic bacteria, especially in deep periodontal pockets. Consequently, the need for novel therapeutic approaches has increased the interest in bioactive natural extracts, such as that of , known for its anti-inflammatory, antioxidant, and antimicrobial properties.
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