[Interleukin-6 in endemic goiter patients in the south Ural region].

The cytokine and thyroid status was studied in patients with endemic goiter (EG) depending on thyroid function. IL-6 correlated with free T3 levels (a negative relationship) in hyperthyroidism, with IL-2 and IFN-gamma levels in EG patients with euthyroidism, and with IL-1beta, IL-2, IL-8, IL-10, and IFN-gamma in hypothyroidism. The EG patients with high IL-6 levels showed positive relationships to IL-2 and thyroid peroxidase antibodies and a negative relationship to free T3.

[Chromatomass spectrometric determination of free fatty acids in blood serum].

Complete analysis of blood serum free fatty acids was carried out after methylation of the acids in the mixture containing methanol-acetyl chloride 50:1 and subsequent evaluation of their methyl esters using a gas chromatography analyser. Standard mixtures of free fatty acids and their methyl esters were analyzed before study of blood serum free fatty acids; composition of fish-liver oil (Far Eastern mackerel), containing definite fatty acids was also studied. Combination of gas chromatography and mass spectrometry enabled to identify all the free fatty acids and to detect their main characteristics (time of retention, typical mass spectrum).