Publications by authors named "I Lospinuso"
Article Synopsis
- The growing awareness of cognitive impairment and dementia as public health issues has led to global efforts to identify risk factors and prevent these conditions.
- Uric acid, a byproduct of purine metabolism, is being studied for its potential dual role in cognitive health, with some research suggesting high levels may protect against Alzheimer's while other studies show opposite effects.
- This review explores the complex relationship between uric acid metabolism and cognitive function, acknowledging the multifaceted nature of biological interactions involved.
Objectives: The first aim of this study was to assess the predictive power of Tend interval (Te) and non-invasive hemodynamic markers, based on bioimpedance in decompensated chronic heart failure (CHF). The second one was to verify the possible differences in repolarization and hemodynamic data between CHF patients grouped by level of left ventricular ejection fraction (LVEF). Finally, we wanted to check if repolarization and hemodynamic data changed with clinical improvement or worsening in CHF patients.
View Article and Find Full Text PDFUnlabelled: Aging and chronic heart failure (CHF) are responsible for the temporal inhomogeneity of the electrocardiogram (ECG) repolarization phase. Recently, some short period repolarization-dispersion parameters have been proposed as markers of acute decompensation and of mortality risk in CHF patients. Some important differences in repolarization between sexes are known, but their impact on ECG markers remains unstudied.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how head-up and head-down tilt affects the autonomic nervous system and ECG segments in healthy individuals.
- It involves 20 subjects undergoing ECG and hemodynamic measurements at different tilt angles (0°, -45°, +45°, +90°) during controlled breathing.
- Findings reveal changes in heart rate variability, where Low Frequency indicators decreased while High Frequency indicators increased, alongside notable alterations in T wave amplitude related to heart volume during tilting.
Background And Aim: Aortic valve stenosis (AVS) is a well-known risk factor for sudden cardiac death. Therefore, some non-invasive, electrocardiographic markers are capable to stratify the risk of sudden death at rest and during light mental challenge [mini-mental state examination (MMSE) administration].
Method: We compared short period RR, QT and Te intervals variability in 42 candidates to and 12 age-matched hypertensive control patients at rest and during mental challenge.