Publications by authors named "I Lon"
Article Synopsis
- Retroperitoneal fibrosis (RPF) is a rare condition characterized by the development of fibrous tissue in the retroperitoneum, with two main subtypes: vascular and urorenal.
- From 2005 to 2021, a study found 27 patients with the vascular subtype and 11 with the urorenal subtype, highlighting demographic differences.
- The urorenal subtype showed significantly worse kidney function and higher cholesterol levels, while the vascular subtype had a higher prevalence of cardiovascular risk factors like hypertension and diabetes, indicating diagnostic and therapeutic challenges due to symptom diversity.
Retroperitoneal Fibrosis Is Still an Underdiagnosed Entity with Poor Prognosis.
Kidney Blood Press Res
March 2022
Background: Retroperitoneal fibrosis (RPF) is a rare disease characterized by the presence of inflammatory and fibrous retroperitoneal tissue that often encircles abdominal organs including the aorta and ureters. Data on the incidence of this disease are limited.
Summary: The disease may be idiopathic or secondary to infections, malignancies, drugs, or radiotherapy.
Familial paraganglioma may be related to mutations in succinate dehydrogenase (SDH) enzyme complex genes. Among patients with hereditary paraganglioma, SDH subunit B (SDHB) gene mutations are associated with the highest morbidity and mortality related to a higher malignancy rate. We report a family with the c.
View Article and Find Full Text PDFIntroduction: One of the concepts of theranostics in nuclear medicine is peptide receptor radionuclide therapy (PRRT), whereby labeled somatostatin analogs are used for imaging and treating inoperable or disseminated neuroendocrine tumors (NET).
Aim: The aim of the study was to determine the therapeutic efficacy and toxicity of tandem Y /Lu-DOTATATE in patients with disseminated NET in a multicenter trial.
Materials And Methods: 103 patients with NET G1/G2 treated with Y/Lu-DOTATATE (1:1) with amino-acid infusion for nephroprotection were included in the study.