Publications by authors named "I Lerotic"
Background/objectives: Increased systemic concentrations of YKL-40 are seen in various inflammatory conditions. We explored the relationship between the serum YKL-40 concentrations and subsequent disease severity in patients with acute pancreatitis (AP).
Methods: Consecutive adults with AP were prospectively enrolled, and classified as having mild, moderate or severe disease.
Background: Biliary obstruction is a relatively common condition that affects approximately 5 in 1000 people annually. Malnutrition is very common in patients with biliary obstruction and since it is associated with significant morbidity and mortality, it is important to identify factors and mechanisms involved in its development.
Aim: To determine the influence of obstructive jaundice on the hormones controlling appetite and nutritive status.
As the burden of liver disease in the general populace steadily increases, so does the need for both advanced diagnostic and treatment options. Endoscopic ultrasound is a reliable diagnostic and therapeutic method that has an established role, foremost in pancreatobiliary pathology. This paper aims to summarize the growing role of endoscopic ultrasound in hepatology based on the search of the current literature.
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- A study examined liver blood test (LBT) abnormalities in COVID-19 hospitalized patients, finding that 74.9% had deranged LBTs, primarily due to elevated AST, GGT, and ALT levels.
- Analysis showed that higher levels of these liver enzymes, particularly AST, were linked to more severe disease and higher risk of mortality after adjusting for other health factors.
- The findings suggest that monitoring LBTs could help predict serious outcomes in COVID-19 patients.
Gastric cancer is related to high mortality rates and advanced disease stage at the time of diagnosis. Its carcinogenesis is extensively studied and is associated with genetic and epigenetic changes, changed the interaction between tumor and adjacent stromal cells, and changes in the microenvironment molecule status. Neural precursor cell-expressed developmentally down-regulated 9 (NEDD9) affects different signaling proteins and pathways, apoptosis, adhesion, cell migration, and invasiveness.
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