Publications by authors named "I Lena"
Effects of laser treatment on bond strength of epoxy resin and calcium silicate-based sealers: a systematic review and meta-analysis of in vitro studies.
Clin Oral Investig
November 2024
Objective: This study aimed to systematically review the effect of laser treatment on the bond strength of epoxy resin-based and calcium silicate-based endodontic sealers to root dentine.
Methods: The search encompassed four databases: PubMed/MEDLINE, EMBASE, Scopus, and ISI Web of Science. Inclusion criteria were limited to in vitro studies conducted on extracted human teeth evaluating bond strength in megapascals (MPa) of either epoxy resin-based or calcium silicate-based sealers, using the push-out test.
Background: The present study aimed to evaluate the fatigue behavior of teeth filled with a calcium silicate-based sealer (Bio-C Sealer, BC) or an epoxy resin-based sealer (AH Plus, AH), in bulk or associated with gutta-percha as main core material.
Methods: Seventy-two sound human maxillary anterior teeth were initially selected. Sixty of them, were randomly chosen, and had their root canals prepared using nickel-titanium reciprocating instruments, being again randomly assigned to five experimental groups ( = 12): C+ (control + prepared but not filled); BC-B (BC in bulk); BC-GP (BC+ gutta-percha); AP-B (AH in bulk); AP-GP (AH+ gutta-percha).
This laboratory study aimed to evaluate the influence of endodontic sealer and cervical limit of root filling on the discoloration of root canal treated teeth. Bovine incisors were randomly distributed into six experimental groups and control (n=21/group), according to the endodontic sealer used [AH Plus (AP); MTA Fillapex (MF) and Sealer Plus BC (SPB)] and the cervical limit of root filling [dental cervix (DC) or 2 mm in apical direction (2mm-AD)]. Tooth discoloration (ΔE) was evaluated by a digital spectrophotometer using the CIED2000 method.
View Article and Find Full Text PDFObjectives: This study aimed to evaluate the success rate of endodontic treatments performed by undergraduate students and the factors associated with the outcome.
Materials And Methods: A follow-up of 3 to 8 years after root canal filling was carried out in 91 patients. At the follow-up visits, medical and dental history questionnaires were applied along with clinical and radiographic examinations.
Article Synopsis
- Spreading depolarizations (SDs) play a role in various neurological conditions like migraines, epilepsy, and strokes, but the exact mechanisms behind them are not well understood.
- Research shows that activating the NaV1.1 sodium channel in interneurons or stimulating GABAergic interneurons can trigger cortical spreading depression (CSD) in the neocortex, indicating a specific mechanism for CSD initiation in this brain region.
- Gain-of-function mutations in NaV1.1 are linked to familial hemiplegic migraine type-3 (FHM3), and the study highlights the importance of GABAergic interneuron hyperactivity in initiating CSD, which may be relevant to other types of migraines and similar disorders.