MORPHOLOGICAL CHARACTERISTICS OF ANGIOGENESIS IN ADENOCARCINOMA OF COLON.

The study of the process of angiogenesis and microcirculation with the help of modern methods of morphological research including type and maturity of the tumor, location and is considered a problem of special importance and value. The purpose of this research is to study the particularity of angiogenesis and microcirculation in colon adenocarcinomas. The human tissue samples of colon adenocarcinoma (19 cases, 40 observation sites) were studied by light microscopic, electron- microscopic, electron-radiographic and immunohistochemical methods.

Correction of Hormonal and Metabolic Disorders in Male Rats with Developing Experimental Diabetes.

Synthetic radioinert androgen methyltrienolone administered daily for 2 weeks to male rats with severe diabetes led to a sharp increase in blood testosterone and was accompanied by reduction in glucose level due to an increase in tissue sensitivity to insulin. Normalization of plasma testosterone concentration contributed to saturation of active androgen receptors in the myocardium with testosterone; the number of free receptors decreased by 1.8 times.

Β-cells of rats pancreas and their supposed precursors during alloxan diabetes and after the action of Plaferon LB.

Using the methods of light and electron microscopy, pancreas was studied in the experimental model (Rats-30) of alloxan diabetes - one month from alloxan injection and after the action of Plaferon LB (amniotic interferon). Special emphasis was made on display of extra-islet cells. Data obtained suggest that extra-islet cells exist in the rats pancreas with alloxan diabetes.

[Extra-islet cells of pancreas during the diabetes of alloxan and after the action of plaferon].

Using the methods of light and electron microscopy, pancreas was studied in the experimental model of alloxan diabetes (AD) at various times of the experiment (1 and 6 month) at different degrees of AD and after the action of plaferon. The special emphasis was made on display of compensatory changes that is opportunity of occurrence in extra-islet cells special granules, characteristic for insulin producing B-cells. During the development of pathological processes, there were detected intermediate cells including exocrine and endocrine granules.

[The structure of thick filaments on longitudinal sections of rabbit psoas muscle].

By means of electron microscopy the longitudinal sections of chemically skinned fibres of rigorised rabbit psoas muscle have been examined at pH of rigorising solutions equal to 6, 7, 8 (I = 0.125) and ionic strengths equal to 0.04, 0.