Background: The inflammatory response associated with COVID-19 varies with sex, potentially affecting disease outcomes. Males have a higher risk of complications compared to females, requiring an evaluation of differences in inflammatory response severity based on sex.
Objective: To compare clinical data, biochemical biomarkers, and outcomes among hospitalized COVID-19 patients in Latin America and the Caribbean (LA&C) based on sex and to perform a cluster analysis of biomarker profiles for both sexes.
Introduction: Viral infection by SARS-CoV2 is a pandemic affecting over 600 million people worldwide. One of five hospitalized patients may present myocardial injury, strongly associated with disease severity and mortality.
Methodology: Retrospective cross-sectional study of hospitalized COVID-19 patients diagnosed between May 01, 2020, and June 30, 2021, from the database of the Registro Latinoamericano de Enfermedad Cardiovascular y COVID-19 (CARDIO COVID 19-20) with a troponin value recorded during hospitalization.
Shifts in cytosolic pH have been recognized as key signaling events and mounting evidence supports the interdependence between H and Ca signaling in eukaryotic cells. Among the cellular pH-stats, K/H exchange at various membranes is paramount in plant cells. Vacuolar K/H exchangers of the NHX (Na,K/H exchanger) family control luminal pH and, together with K and H transporters at the plasma membrane, have been suggested to also regulate cytoplasmic pH.
View Article and Find Full Text PDFEcological interactions are a key component of biodiversity, essential for understanding ecosystem services and functioning. Recording and quantifying ecological interactions is challenging, frequently requiring complex logistics and substantial effort in the field. Camera traps are routinely used in ecology for various applications, and have proven to be an excellent method for passive and non-invasive sampling of plant-animal interactions.
View Article and Find Full Text PDFPurpose: This work aimed to evaluate the impact of a guaranteed access program to imatinib on the survival of patients with Chronic Myeloid Leukemia.
Methods: We carried out a retrospective, observational, and analytical study of the database of patients diagnosed with Chronic Myeloid Leukemia of the Instituto Nacional de Cancerología and the Hospital General de México Dr. Eduardo to assess overall survival based on guaranteed access or not to imatinib.