[Anemia and gastroesophageal reflux disease in patients with coronary heart disease].

We studied the relationship between anemia and chronic diseases of the upper gastrointestinal tract in patients with CHD. Patients with CHD and gastroesophageal reflux disease (GERD) had the lowest hemoglobin levels and erythrocyte counts in the absence of pronounced independent effect of GERD. This finding suggests common pathogenesis of CHD, GERD and anemia in patients with coronary problems.

[Polycomb and trithorax control genome expression by determining the alternative epigenetic states of chromatin for key developmental regulators].

The Polycomb (PcG) and Trithorax (TrxG) group proteins are essential for development in all multicellular organisms. Mutations of the PcG and TrxG genes act as early embryonic lethals, while their overexpression correlates with malignancies. Comparative genome analysis showed that PcG and TrxG form a binary regulatory system that functions as an epigenetic rheostat to determine the threshold levels of extracellular signals affecting the expression levels of key developmental genes.

[Periodic medical examinations: problem of concordance].

From bioethics and contemporary medical legislation viewpoints, the authors consider a topic of periodic medical examinations and possibility of concordance between doctor and patient. Opinion is that in order to gain concordance and higher efficiency of the examinations, the doctor should separate occupational examination function from medical function.

[Interrelationship between lower limb varicosity, the grade of connective tissue dysplasia and atrial fibrillation in patients with coronary artery disease].

Purpose: To determine interrelationship between lower limb varicosity, the clinical grade of non-differentiated dysplasia of the connective tissue and atrial fibrillation in patients with coronary artery disease (CAD).

Material And Methods: Altogether 156 coronary patients were examined. Persistent atrial fibrillation was present in 58 and chronic in 38 patients.