Long range segmentation of prokaryotic genomes by gene age and functionality.

Bacterial and archaeal genomes encompass numerous operons that typically consist of two to five genes. On larger scales, however, gene order is poorly conserved through the evolution of prokaryotes. Nevertheless, non-random localization of different classes of genes on prokaryotic chromosomes could reflect important functional and evolutionary constraints.

Long range segmentation of prokaryotic genomes by gene age and functionality.

Bacterial and archaeal genomes encompass numerous operons that typically consist of two to five genes. On larger scales, however, gene order is poorly conserved through the evolution of prokaryotes. Nevertheless, non-random localization of different classes of genes on prokaryotic chromosomes could reflect important functional and evolutionary constraints.

Patterned Drug-Eluting Coatings for Tracheal Stents Based on PLA, PLGA, and PCL for the Granulation Formation Reduction: In Vivo Studies.

Expandable metallic stent placement is often the only way to treat airway obstructions. Such treatment with an uncoated stent causes granulation proliferation and subsequent restenosis, resulting in the procedure's adverse complications. Systemic administration of steroids drugs in high dosages slows down granulation tissue overgrowth but leads to long-term side effects.

[Age reactivity of the organism of patients for treating bone limits.].

The purpose of the study is to find out how reducing the reactivity of the organism in patients of different age groups affects the duration of treatment of fractures of the Shin bones. The Analyzed data 1 382 case histories of patients of different age with fractures of the tibia in the treatment by Ilizarov for the past 42 years. Instrumental in the process of treatment in 98 patients with fractures of Shin bones the studied indicators of muscle strength, oxygen tension in the tissues, the load on the limb, micromotion of bone fragments, the speed of regional blood flow and blood flow in the middle cerebral artery.

Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site.

Disrupted in schizophrenia 1 (DISC1) has been identified as a putative risk factor for schizophrenia and affective disorders through study of a Scottish family with a balanced (1;11) (q42.1;q14.3) translocation, which results in the disruption of the DISC1 locus and cosegregates with major psychiatric disease.