Publications by authors named "I L S Prada"

Africa's dual burden of rising incidence of infectious diseases and increasing prevalence of non-communicable diseases (NCDs), such as cardiovascular diseases and diabetes, demands innovative approaches to disease surveillance, response, and cross-border health management in response to growing economic integration and global connectivity. In this context, we propose a discursive framework for the development and implementation of a multi-disease digital health passport (MDDHP) in Africa. The MDDHP would serve as a secure platform for storing and sharing individual health data, offering a comprehensive solution to track and respond to infectious diseases, facilitate the management of NCDs, and improve healthcare access across borders.

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The amputation of a limb in quadrupeds can overload the remaining limbs, especially the contralateral one. The compensatory effort is especially high if it is a forelimb. It is, therefore, important to objectively know the changes in weight redistribution that occur in the animal while walking and standing still.

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Tearing of the cranial cruciate ligament causes hindlimb lameness in dogs. Different surgical procedures have been proposed to treat this condition. In this study, two different TTA-based techniques and implants were compared.

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Article Synopsis
  • - Researchers discovered that extracellular vesicles (EVs) from astrocytes play a key role in regulating calcium levels within neurons, specifically highlighting transglutaminase-2 (TG2) as an important component on these EVs.
  • - When hippocampal neurons were treated with these TG2-containing EVs, calcium concentrations ([Ca]) increased dramatically, whereas EVs lacking TG2 did not produce this effect, indicating TG2’s significance in calcium dynamics.
  • - The study suggests that reactive astrocytes can influence neuronal activity and potentially affect synaptic functions during inflammation in the brain by modulating calcium levels through the release of TG2-containing EVs.
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