Publications by authors named "I L S Brandao"

Article Synopsis
  • Apoferritin-based systems are being researched for their potential use in vaccine delivery against viral diseases, offering benefits like enhanced stability and reduced side effects.
  • The study focuses on using a specific tumor antigen, EGFRvIII peptide, in combination with apoferritin to create a potentially effective peptide vaccine for cancer treatment.
  • The results indicate that varying the concentration of the peptide affects immune responses and antibody production, which is crucial for ensuring the safety and effectiveness of the vaccine formulation.
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We investigate the effects of solvents on the geometry, absorption spectrum, and first hyperpolarizability of six push-pull molecules, each containing a 4,5-dicyanoimidazole group as an electron acceptor and a N,N-dimethylamino group as an electron donor, with systematically extended π-conjugated systems. Geometry optimizations in dichloromethane, methanol, water, and formamide under normal thermodynamic conditions were performed using the average solvent electrostatic configuration-free energy gradient method, which employs a discrete solvent model. The conformational structure of molecules is moderately affected by the environment, with the π-conjugated system becoming more planar in protic solvents.

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Introduction: Most lung cancers are diagnosed at an advanced stage. Common metastatic sites include the brain, bone, liver and adrenal glands. Ocular metastases, however, are extremely rare.

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