Publications by authors named "I L Notkola"
Introduction: The present study examines how trends in the prevalence of asthma during the past three decades associate with hospitalization and mortality during the same period.
Methods: Altogether 54 320 subjects aged 25-74 years were examined in seven independent cross-sectional population surveys repeated every five years between 1982 and 2012 in Finland. The study protocol included a standardized questionnaire on self-reported asthma, smoking habits and other risk factors, and clinical measurements at the study site.
Objective: The aim of this study was to analyze brain pathologies which cause dementia in the oldest old population.
Methods: All 601 persons aged ≥85 years living in the city of Vantaa (Finland), on April 1st, 1991 formed the study population of the Vantaa85 + study, 300 of whom were autopsied during follow-up (79.5% females, mean age-at-death 92 ± 3.
Background: The study examines the predictive value of chronic bronchitis for all cause and cause-specific hospitalizations and for mortality during the last three decades.
Methods: The study population consists of altogether 47 896 men and women aged 25-74 years who participated in the National FINRISK Study between 1982 and 2007. The study protocol included a standardized questionnaire on the symptoms of chronic bronchitis, smoking habits and other risk factors and clinical measurements at the study site.
Introduction And Aims: Adverse childhood experiences and their accumulation over childhood have negative outcomes to children, yet earlier findings on the independent effect of parental substance abuse seem inconsistent. Our aims were to examine: (i) whether parental substance abuse is associated with children's mental disorders in mid-childhood (7-12 years) and mental disorders and own substance use in adolescence (13-17 years); and (ii) whether children are affected differently by a mother or father's substance abuse.
Design And Methods: A register-based longitudinal data on a complete birth cohort of children born in Finland in 1991 (n = 65 117) and their biological parents.
Background: Finnish type of hereditary gelsolin amyloidosis (AGel amyloidosis) is an autosomal dominant disorder. Until recently, there has only been little knowledge of fatal complications of the disease and its possible impact on the patients' life span.
Methods: We identified 272 deceased patients based on patient interviews and genealogical data.