Zh Nevrol Psikhiatr Im S S Korsakova
April 2011
We have analyzed the efficacy of nootropic drug pantogam in the treatment of hyperkinetic disorders in children aged 6-12 years. The results of the randomized placebo-controlled trial demonstrated the decrease of major symptoms of hyperkinetic disorders (inattention, hyperactivity, impulsivity), comorbid mental and behavior disorders, the improvement of cognitive functions in the group of children treated with pantogam during 6 weeks and the absence of significant changes in the placebo group. It has been concluded that pantogam is effective in the treatment of hyperkinetic disorders in children.
View Article and Find Full Text PDFA historical review of allantoin research is presented. An increased allantoin level in the trophoblast and serum of pregnant women has been demonstrated. Allantoin concentration decreased in placental tissues and increased in the serum in developing placental insufficiency.
View Article and Find Full Text PDFTemporal relations were analyzed between the VEP components in the occipital and central cortical areas in 7 and 10-year-old boys with normal intelligence, with mental retardation, and with debile oligophrenia in three experimental sessions with different instructions. It was found out that the intrahemispheric relations of the isopolar VEP components to a flash and patterned stimulus similar to those in adult persons developed in healthy children only to the age of 10 years. In children with intellectual deficiency such relations were distorted both in perception of the flash and patterned visual stimuli and during mental representation of the latter.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
August 1994
Visual evoked potentials (VEP) to flash and patterned visual stimuli have been recorded from occipital and central brain regions in 7-8-year-old boys with normal intellect (20 cases), with mental retardation (15 cases) and with oligophrenia of a debile degree (27 cases). A significant elongation of late-component latency has been revealed in motor brain areas VEP in oligophrenia group compared to normal subjects. A negative correlation between P190 component latency of motor area VEP to patterned visual stimulus and general and non-verbal intellectual indices has been stated in full right-handed subjects with intellectual deficiency.
View Article and Find Full Text PDFA study of 52 patients with hypertensive disease (grade II, age--from 30 to 50 years; men--32, women--24) using functional tests with physical loads revealed that pronounced hemodynamic changes were seen in patients with the hyperkinetic type of hemodynamics. Obsidan and prazosin reduced the degree of responses to physical loads, economy of energy expenses, increased tolerance to physical work. Association of pharmacological tests with functional physical loads in patients with hypertensive disease allows to realize selection of hypotensive drugs depending on the hemodynamic variant of the course of the pathological process and evaluate the adequacy of dosages for treatment courses.
View Article and Find Full Text PDF