Publications by authors named "I L Khalif"

Background: Irritable bowel syndrome (IBS) is one of the most common functional disorders of the gastrointestinal tract. According to Russian guidelines, a standard examination using laboratory and instrumental evaluation methods, including colonoscopy, should be performed to establish the diagnosis of IBS.

Aim: To characterize the Russian population of IBS patients.

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One of the dysbioses often observed in Crohn's disease (CD) patients is an increased abundance of (10-100 fold compared to healthy individuals) (Gevers et al., 2014). The data reported is a large-scale proteome profile for isolates collected from CD patients and healthy individuals.

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Aim: To assess the effectiveness of conservative treatment of Crohn's disease (CD) with perianal lesions.

Materials And Methods: The study included 20 patients with CD with perianal fistulae. Prior to the start of conservative therapy, 7 patients underwent fistulae drainage with setton placement.

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Article Synopsis
  • Crohn's disease is linked to imbalances in gut bacteria, specifically with an increase in certain types of E. coli, and more research is needed to understand their role.
  • A metagenomic study of Crohn's patients showed that the gut microbiomes varied significantly between individuals, revealing high genetic diversity in E. coli strains.
  • The findings suggest that understanding the genetic diversity of these bacteria can help develop better prevention and treatment options for Crohn's disease.
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