Resting beat-to-beat blood pressure variability in humans: role of alpha-1 adrenergic receptors.

Purpose: Resting beat-to-beat blood pressure variability is a strong predictor of cardiovascular events and mortality. However, its underlying mechanisms remain incompletely understood. Given that the sympathetic nervous system plays a pivotal role in cardiovascular regulation, we hypothesized that alpha-1 adrenergic receptors (the main sympathetic receptor controlling peripheral vasoconstriction) may contribute to resting beat-to-beat blood pressure variability.

The association of lung consolidation and respiratory pathogens identified at weaning on the growth performance of beef on dairy calves.

This observational study evaluated the relationship between lung consolidation observed at weaning and calf ADG, and the association of pathogen shedding at weaning on ADG in beef × dairy calves up to 238 d. Beef × Holstein calves (n = 143) were sourced from 2 dairies. Calves were managed in 3 cohorts and fed milk replacer and calf starter preweaning.

Conventional methods and electronic apical locator in determining working length in different primary teeth: systematic review and meta-analysis of clinical studies.

Aim: The aim of the current systematic review was to investigate differences in the measurement of working length in primary teeth between electronic apex locators (EAL) and radiographic methods (conventional radiography [CR] and digital radiography [DR]).

Methods: A systematic search was conducted in six electronic databases (Medline via PubMed, Web of Science, Science Direct, Virtual Health Library, Scopus and Cochrane Database of Systematic Reviews). Gray literature and reference lists of included studies were also examined.

How Habitat Simplification Shapes the Morphological Characteristics of Ant Assemblages (Hymenoptera: Formicidae) in Different Biogeographical Contexts.

Human-driven changes in land cover and use can significantly impact species ants community structures, often leading to a decline in taxonomic diversity or species homogenization. Ant morphology, used as a proxy for ecological function, offers a valuable framework for understanding the effects of anthropogenic disturbances on ant diversity. This study explored the morphological diversity of ant assemblages in agricultural ecosystems and secondary forests in Italy and the Brazilian Amazon, analyzing how these communities are structured and adapted to different environments.

Copy Number Variation in Asthma: An Integrative Review.

Asthma is a complex disease with varied clinical manifestations resulting from the interaction between environmental and genetic factors. While chronic airway inflammation and hyperresponsiveness are central features, the etiology of asthma is multifaceted, leading to a diversity of phenotypes and endotypes. Although most research into the genetics of asthma focused on the analysis of single nucleotide polymorphisms (SNPs), studies highlight the importance of structural variations, such as copy number variations (CNVs), in the inheritance of complex characteristics, but their role has not yet been fully elucidated in asthma.