Integrin α11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression.

Background: Cancer-associated fibroblasts (CAFs) were shown to be important for tumour progression in head and neck squamous cell carcinomas (HNSCCs). Their heterogeneity and lack of specific markers is increasingly recognized. Integrin α11 was recently shown to be expressed by CAFs and might serve as a specific CAF marker.

[Acute cholecystitis with and without gallstones. The frequency of surgical interventions in Frederiksberg during the period 1978-1988].

In Frederiksberg Hospital in Denmark the therapeutic procedure for acute cholecystitis requiring operation was altered in 1983. Since then, acute cholecystitis has constituted 15% of all cholecystectomies which corresponds to 15 per 100,000 of the population per annum. 12% of these cases were without stones in the gallbladder.

Early secondary suture versus healing by second intention of incisional abscesses.

A controlled trial was set up to compare the treatment of wound abscesses, occurring after laparotomy, with either early secondary suture combined with cefuroxime and metronidazole given intravenously or by healing by second intention. The secondary suture was performed two days after wound drainage and resulted in a significant reduction (p less than 0.01) in healing time without complications.

Bronchial carcinoid tumours. A clinicopathologic study of 82 cases.

A clinical and "blind" histologic review of 82 cases of bronchial carcinoid tumour is presented. The malignant potential of the tumours was only partly predictable from their histologic appearance. Histologically 65 of the tumours were typical benign carcinoids.

Pattern of pain, duct morphology, and pancreatic function in chronic pancreatitis. A comparative study.

In 101 patients with suspected or definite chronic pancreatitis a pancreatic function test, endoscopic retrograde pancreatography, and an interview with special regard to pain were performed. Decrease in pancreatic function was correlated to dilatation of the pancreatic duct system. However, no correlation between the duct morphology and the severity of pain was found.