Publications by authors named "I L Arrais Ribeiro"
Background: Active commuting benefits both individual and planetary health. Estimating commuting behavior is desirable, although very challenging in large and regionally relevant nations like Brazil.
Methods: This review (CRD42023431054) included observational studies that estimated prevalence of active commuting in Brazil for adults (≥18 y).
Article Synopsis
- The Developmental Origins of Health and Disease (DOHaD) concept links early adverse conditions, like maternal protein restriction, to chronic diseases, specifically prostate cancer (PCa).
- The study investigated the expression of piwi-interacting RNAs (piRNAs) in the ventral prostate of rat offspring affected by maternal malnutrition, revealing developmental delays and altered tissue structures.
- Findings suggest that maternal malnutrition influences piRNA expression, which may have long-term effects on prostate health and increase the risk of disorders as the offspring age.
Article Synopsis
- * The p.Ala1035Val variant is the most common in Portugal and is linked to a potential SNP (p.Ile858Val) that may affect disease progression.
- * Research using in vitro models reveals that the p.Ala1035Val variant, especially when combined with p.Ile858Val, shows decreased lysosomal trafficking similar to p.Ile1061Thr, suggesting the need for new therapeutic approaches.
Article Synopsis
- - The study aimed to determine how common fatigue is in adults with colorectal cancer (CRC) and to examine how fatigue relates to various sociodemographic and clinical factors.
- - Among 241 CRC patients, moderate fatigue was most common, affecting 49.3% of participants, with newly diagnosed patients experiencing the highest levels of severe fatigue.
- - Factors such as having multiple health issues, severe pain, and mood disorders were associated with increased fatigue, highlighting the need for early screening and management of fatigue in these patients.