Publications by authors named "I Kuan Sam"

Background: Seasonal influenza illness and acute respiratory infections can impose a substantial economic burden in low- and middle-income countries (LMICs). We assessed the cost of influenza illness and acute respiratory infections across household income strata.

Methods: We conducted a secondary analysis of data from a prior systematic review of costs of influenza and other respiratory illnesses in LMICs and contacted authors to obtain data on cost of illness (COI) for laboratory-confirmed influenza-like illness and acute respiratory infection.

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Introduction: There is a lack of real-world evidence on direct comparisons between COVID-19 vaccines in multiethnic low- and middle-income settings. Cancer patients have an impaired vaccine response due to the disease itself or the effects of treatment. Hence, identifying the best vaccine to use for cancer patients is important.

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Background: In 2008-2010, Malaysia experienced a nationwide chikungunya virus (CHIKV) outbreak caused by the Indian Ocean lineage E1-226V (valine) variant, adapted to Aedes albopictus. In 2017-2022, transition to an E1-226A (alanine) variant occurred. Ae.

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Article Synopsis
  • Common cold coronaviruses (ccCoVs) and influenza viruses are common causes of upper respiratory infections, but the health effects of ccCoV infections are not well understood.
  • A study involving 3,935 outpatients compared symptoms and outcomes between ccCoV and influenza infections, finding that sore throat, nasal discharge, headache, and myalgia were more common in ccCoV, while fever was prevalent in influenza cases.
  • Patients with underlying health conditions had increased primary care visits for respiratory symptoms following both infections, suggesting that managing these comorbidities is crucial to reduce negative health impacts.
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Cytomegalovirus (CMV) infection is one of the common complications which can lead to significant morbidity and mortality in patients after allogeneic hematopoietic stem cell transplantation (HSCT). As the seroprevalence of CMV infection in Malaysia is high, this study aims to determine the prevalence of CMV infection in patients post HSCT and to evaluate the associated risk factors. Patients who underwent allogeneic HSCT in adult ward from 2008 to 2020 at a tertiary teaching hospital in Kuala Lumpur, Malaysia were studied retrospectively.

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