Publications by authors named "I Kilicaslan"
Background/aim: Sarcoidosis is a multisystem disorder that affects many organs, including the kidneys. This single-center retrospective study investigated the clinical, pathological, and laboratory findings of patients with kidney sarcoidosis who were treated with immunosuppressives.
Materials And Methods: Twenty-three patients with biopsy-confirmed kidney sarcoidosis were included.
Karyomegalic interstitial nephritis (KIN) is a rare entity associated with biallelic FAN1 (FANCD2/FANCI-Associated Nuclease 1) gene variants. In FAN1-related KIN, abnormal liver function tests and respiratory involvement are common, in addition to chronic kidney disease. Karyomegalic changes have also been reported in many other organs in patients with FAN1-related KIN in various studies.
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- Fentanyl, a commonly used opioid in emergency departments, may significantly prolong QT intervals in patients, particularly females over 40.
- A study monitored 109 patients receiving intravenous fentanyl, showing a notable increase in QT values at 5, 15, 30, and 60 minutes after administration, with the most significant change occurring at 30 minutes.
- Although the QT prolongation was evident, no patients experienced serious arrhythmias during the observation period, highlighting the need for caution in using fentanyl for those at risk of heart complications.
Background/aim: In this prospective study, we aimed to investigate the association of serum (s) and urine (u) IP-10, galectin-9, and SIGLEC-1 with disease activity in patients with systemic lupus erythematosus (SLE).
Materials And Methods: Sixty-three patients with active SLE (31 renal, 32 extrarenal) were included. Thirty patients with inactive SLE (15 renal, 15 extrarenal), 17 with renal active AAV, and 32 healthy volunteers were selected as control groups.