Publications by authors named "I Kaya"

Multiomics analysis of single tissue sections using matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) provides comprehensive molecular insights. However, optimizing tissue sample preparation for MALDI-MSI to achieve high sensitivity and reproducibility for various biomolecules, such as lipids, -glycans, and tryptic peptides, presents a significant challenge. This study introduces a robust and reproducible protocol for the comprehensive sequential analysis of the latter molecules using MALDI-MSI in fresh-frozen rodent brain tissue samples.

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Background: The effect of conservative treatments on sleep quality in carpal tunnel syndrome is unclear.

Purpose: Comparing the effect of splinting and kinesiotaping in carpal tunnel syndrome on functional status, pain, grip strength, nerve cross-sectional area and sleep quality.

Study Design: Randomized controlled study.

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Objective: This study aimed to assess the efficacy of a novel modified asymmetric chondro-perichondrial island graft in tympanoplasty. The design features a longer anterior segment compared to the posterior segment, addressing limitations of symmetrical grafts. We investigated the impact of this modified graft on hearing improvement and graft success rates in patients undergoing tympanoplasty surgery.

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Article Synopsis
  • The study investigates different strategies for venoarterial extracorporeal membrane oxygenation (V-A ECMO) in patients, examining the effectiveness of various cannulation sites and the use of intra-aortic balloon pump (IABP).
  • Researchers categorized patients into two main groups: those receiving isolated V-A ECMO and those receiving V-A ECMO with IABP, and further divided them based on cannulation sites (e.g., central, axillo-femoral).
  • Results showed no significant differences in organ perfusion across the different cannulation sites or with IABP support, suggesting that the choice of cannulation site should be tailored to individual patient needs rather than based on a one-size-fits-all approach
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Article Synopsis
  • New surgical techniques known as transorbital neuroendoscopic surgery have been developed to access the orbit and intracranial cavity, particularly via the superior eyelid route.
  • This study involved performing transorbital endoscopic dissections on 4 cadavers to explore the feasibility of this approach in identifying arterial structures.
  • Results showed that the M1 and M2 segments of the middle cerebral artery could be accessed using a 0-degree endoscope, suggesting this method could offer a new surgical alternative for certain cranial conditions.
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