Publications by authors named "I Kanakakis"
Background: Coronary computed tomography angiography (CCTA) in patients with post-coronary artery bypass graft (CABG) has a high diagnostic accuracy for visualization of grafts. Invasive coronary angiography (ICA) in patients with CABG is associated with increased procedural time, contrast agent administration, radiation exposure, and complications, compared with non-CABG patients. The aim of this multicenter, randomized controlled trial was to compare the strategy of CCTA-guided ICA versus classic ICA in patients with prior CABG.
View Article and Find Full Text PDFPurpose: Atrial fibrillation (AF) and heart failure (HF) are common and commonly coexisting cardiovascular diseases in hospitalized patients. We report the absolute number and interrelation between AF and HF, assess the daily burden of both diseases on the healthcare system, and describe the medical treatment in a real-world, nationwide conducted snapshot survey.
Methods: A questionnaire was equally distributed to various healthcare institutions.
Despite major advances in pharmacotherapy and interventional procedures, coronary artery disease (CAD) remains a principal cause of morbidity and mortality worldwide. Invasive coronary imaging along with the computation of hemodynamic forces, primarily endothelial shear stress and plaque structural stress, have enabled a comprehensive identification of atherosclerotic plaque components, providing a unique insight into the understanding of plaque vulnerability and progression, which may help guide patient treatment. However, the invasive-only approach to CAD has failed to show high predictive value.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the effectiveness of high-sensitivity C-reactive protein (hsCRP) and carotid ultrasound in determining eligibility for cholesterol-lowering treatments, focusing on differences between men and women.
- It analyzes data from two Greek cohorts to estimate the risk of atherosclerotic cardiovascular disease (ASCVD) using specific tools and identifies where carotid plaque and elevated hsCRP levels influence treatment eligibility.
- Results show that women initially have lower eligibility for treatment, but when accounting for carotid plaque and hsCRP, their eligibility significantly increases compared to men, highlighting the need for further research on treatment impacts in these populations.