[Effect of alpha 2-macroglobulin on indices of the proteolysis system and organ blood flow in tourniquet shock].

It was shown that alpha 2-macroglobulin (50 mg/kg, 30 min before revascularization of previously ischemized extremities) significantly inhibits the blood serum proteolytic activity and exerts similarly to contrykal (10,000 U/kg) the correcting effect on the level of arterial blood pressure and parameters of the blood flow in the kidneys, intestine and previously ischemized extremities.

[Comparative analysis of the changes in the organic blood flow in the brain, kidneys, intestines and hindlimbs of cats as affected by adrenaline and noradrenaline].

In experiments on anesthetized cats by using the method of hydrogen clearance it was found that noradrenaline and adrenaline at doses of 0.01-10 micrograms/kg intravenously produced dose-dependent various changes in organ blood flow that were caused by differences in the action on adrenoreceptors and the degree of hypertensive reaction. The vessels of the intestine and kidneys possessed the highest sensitivity to noradrenaline and the cerebral vessels had the least sensitivity.

[Effect of noradrenaline and angiotensin II on the brain and kidney blood supply with changes in systemic arterial pressure].

Hydrogen clearance was used in experiments on anesthetized cats to demonstrate that intravenous infusions of noradrenaline induced an increase in cerebral blood supply and reduction of renal blood flow both in anesthetized animals and in the presence of hypotension. In these conditions, angiotensin II lowered the cerebral and renal blood flow. Hypotension enhanced the reactions of the cerebral and renal blood flow to the action of vasopressor agents.