[Role of the liver in formation of the natriuretic factor].

A response to an increase in the liquid volume and the level of the natriuretic factor in the blood were studied 30 h, 3, 7, 14 and 28 days after removal of 2/3 of the liver mass in rats. The state of the liver was studied in parallel in the same periods. Volumetric natriuresis in rats and the NUF level in the blood after partial hepatectomy decreased sharply and increased gradually by the 28th day, i.

[Morphologic signs of adaptation of the microcirculatory bed of the liver to denervation].

The effect of mixed denervation on the hepatic microcirculatory bed was studied in dogs and rats. Seven days after denervation, dilated sinusoid capillaries and spaces around the sinuses (Disse's space), disorders in structure of the sinusoid reticular carcass were revealed in the liver of the dogs and rats. The labelled nuclei index in the stellate endotheliocytes is statistically increasing; one month later, in the sinusoid wall the number of cells containing glicosaminoglicanes in the cytoplasm is increasing, outgrowth of the reticular fibres in the perisinusoid spaces and reorganization of the reticular type of the hepatic stroma from the radial into the alveolar one is noted.