Publications by authors named "I K Ber"
Article Synopsis
- This study focused on vaccine hesitancy in Israel's ultraorthodox Jewish community, where many people are hesitant to get vaccinated against COVID-19.
- Researchers developed and validated a questionnaire to understand factors influencing the decision to receive the fourth COVID-19 vaccine dose, employing a mixed-methods approach.
- Key findings showed that religious authority, health information sources, and perceptions of vaccine safety and effectiveness were significant factors, with about 46% of participants indicating intention to get the fourth dose.
Neurodegenerative dementias have a profound impact on higher-order cognitive and behavioural functions. Investigating macroscale functional networks through cortical gradients provides valuable insights into the neurodegenerative dementia process and overall brain function. This approach allows for the exploration of unimodal-multimodal differentiation and the intricate interplay between functional brain networks.
View Article and Find Full Text PDFAssociation of Changes in Cerebral and Hypothalamic Structure With Sleep Dysfunction in Patients With Genetic Frontotemporal Dementia.
Neurology
December 2024
Background And Objectives: Sleep dysfunction is common in patients with neurodegenerative disorders; however, its neural underpinnings remain poorly characterized in genetic frontotemporal dementia (FTD). Hypothalamic nuclei important for sleep regulation may be related to this dysfunction. Thus, we examined changes in hypothalamic structure across the lifespan in patients with genetic FTD and whether these changes related to sleep dysfunction.
View Article and Find Full Text PDFAssociation of Initial Side of Brain Atrophy With Clinical Features and Disease Progression in Patients With Frontotemporal Dementia.
Neurology
December 2024
Background And Objectives: Pathogenic variants in the gene cause frontotemporal dementia (FTD-) with marked brain asymmetry. This study aims to assess whether the disease progression of FTD- depends on the initial side of the atrophy. We also investigated the potential use of brain asymmetry as a biomarker of the disease.
View Article and Find Full Text PDFFrontoparietal network integrity supports cognitive function in pre-symptomatic frontotemporal dementia: Multimodal analysis of brain function, structure, and perfusion.
Alzheimers Dement
December 2024
Introduction: Genetic mutation carriers of frontotemporal dementia can remain cognitively well despite neurodegeneration. A better understanding of brain structural, perfusion, and functional patterns in the pre-symptomatic stage could inform accurate staging and potential mechanisms.
Methods: We included 207 pre-symptomatic genetic mutation carriers and 188 relatives without mutations.