Publications by authors named "I Jurisica"

Article Synopsis
  • MatrixDB is a curated database specializing in interactions involving extracellular matrix (ECM) components like proteins and proteoglycans, designed for enhanced data export and access.
  • The updated version features over twice as many manually curated interactions, incorporates high-confidence predicted interactions, and categorizes ECM proteins from five species for better computational analysis.
  • It includes new datasets for generating specific ECM networks and integrates biological pathways for a comprehensive view of ECM interactions, accessible for free online.
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Epithelioid sarcoma (ES) is a rare tumor hallmarked by the loss of INI1/SMARCB1 expression. Apart from this alteration, little is known about the biology of ES. Despite recent advances in treatment, the prognosis of ES remains unsatisfactory.

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Background: Exercise can be used as a model to understand immunometabolism. Biological data on elite athletes are limited, especially for female athletes, including relevant data on acute-phase proteins and amino acid metabolism.

Methods: We analyzed acute-phase proteins and amino acids collected at South American, Pan-American, and Olympic Games for 16 Olympic sports.

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Introduction: Kidney transplantation is the optimal treatment for end-stage kidney disease; however, premature allograft loss remains a serious issue. While many high-throughput omics studies have analyzed patient allograft biospecimens, integration of these datasets is challenging, which represents a considerable barrier to advancing our understanding of the mechanisms of allograft loss.

Methods: To facilitate integration, we have created a curated database containing all open-access high-throughput datasets from human kidney transplant studies, termed NephroDIP (Nephrology Data Integration Portal).

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