Noninvasive Optical Sensing of Aging and Diet Preferences Using Raman Spectroscopy.

Effective dietary strategies and interventions for monitoring dietary exposures require accurate and noninvasive methods to understand how diet modulates health and risk of obesity; advances in technology are transforming the landscape and enabling more specific tailored approaches to nutritional guidance. This study explores the use of Raman spectroscopy (RS), a noninvasive and nondestructive analytical technique, to identify changes in the mice skin in response to constant dietary exposures. We found that RS is highly accurate to determine body composition as a result of habitual dietary patterns, specifically Vegan, Typical American, and Ketogenic diets, all very common in the US context.

Two different complement Factor B (Bf) alleles of the orangutan major histocompatibility complex (MHC) are also conserved in chimpanzee and humans showing importance in primate immunity.

Background: Major Human Histocompatibility complex (MHC or HLA in humans) has been associated to autoimmune diseases. However, only statistical phenomenological and no pathogenetic description has been reached after decades. This shows that MHC single locus association studies are probably useless for HLA/diseases association.

HLA-G high-expressor 3'UTR markers are linked to gastric cancer development and survival.

Gastric cancer ranks fifth in both world prevalence and lethality, with a 5-year survival of less than 30%. HLA-G, a non-classical class I HLA gene, has emerged as a potential marker for cancer susceptibility and prognosis due to its immunomodulatory properties. Its level of expression is regulated by polymorphisms in the 3' untranslated region (3'UTR) polymorphisms, which form various combined haplotypes (UTR-1 to -9).

The Immune Modulation Full Allele Is Associated with Gastric Adenocarcinoma Development.

The Human Leukocyte Antigen (HLA) system contains a set of genes involved at many levels in the innate and adaptive immune response. Among the non-classical HLA class I genes, HLA-G stands out for the numerous studies about its pivotal role in regulating/modulating immune responses. Also, its involvement in extravillous cytotrophoblast function, viral infections, autoimmunity, and cancer has been extensively documented.

Contemporary applications of vibrational spectroscopy in plant stresses and phenotyping.

Plant pathogens, including viruses, bacteria, and fungi, cause massive crop losses around the world. Abiotic stresses, such as drought, salinity and nutritional deficiencies are even more detrimental. Timely diagnostics of plant diseases and abiotic stresses can be used to provide site- and doze-specific treatment of plants.