Publications by authors named "I Johnsson"
Article Synopsis
- Plaque psoriasis (PsO) is a chronic condition that requires long-term treatment, making drug persistence crucial for ongoing effectiveness and patient tolerance.
- This study analyzed treatment persistence and discontinuation rates of various biologic agents and apremilast among PsO patients in Finland and Sweden, focusing on data from 2008-2020.
- Results showed that guselkumab and ustekinumab had the highest persistence rates, with 90% and 85% of patients continuing treatment for at least one year, and guselkumab had lower discontinuation rates compared to other treatments.
This study aimed to investigate how maternal birthweight is related to early pregnancy obesity, gestational diabetes mellitus (GDM), and offspring birthweight. Females born term and singleton in Sweden between 1973 and 1995 (N = 305,893) were studied at their first pregnancy. Information regarding their birthweight, early pregnancy body mass index, and pregnancy complications was retrieved from the Swedish Medical Birth Register, as were data on their mothers and offspring.
View Article and Find Full Text PDFAim: To investigate whether a high birthweight was associated with an increased proportion of body fat or with impaired glucose tolerance in adulthood.
Methods: Our cohort comprised 27 subjects with birthweights of 4500 g or more, and 27 controls with birthweights within ±1 standard deviation scores, born at Uppsala University Hospital 1975-1979. The subjects were 34-40 years old at the time of study.
Aim: This study investigated whether a high birth weight was associated with increased risk factors for cardiovascular disease when Swedish adults reached 34-40.
Methods: We studied 27 subjects born at Uppsala University Hospital in 1975-1979, weighing at least 4500 g, and compared them with 27 controls selected by the Swedish National Board of Welfare with birth weights within ±1 standard deviations scores and similar ages and gender. The study included body mass index (BMI), blood pressure, lipid profile, haemoglobin A1c (HbA1c), C-reactive protein (CRP) and high-frequency ultrasound measurements of intima-media thickness, intima thickness (IT) and intima:media ratio of the carotid and radial arteries.
Background: The association between low birth weight and adult disease is well known. Less is known on long-term effects of high birth weight.
Objective: This study aims to investigate whether a high birth weight increases risk for adult metabolic disease.