Publications by authors named "I J Bruce"

Background: The insertion of a tracheostomy is an established technique used to wean patients off ventilatory support, manage secretions in complex conditions, and as a potentially life-saving procedure to bypass upper airway obstruction. Life-threatening complications during aftercare are not uncommon and may be influenced by a lack of education of carers or healthcare providers of children and young people living with a tracheostomy. Education programmes designed and supported by the National Tracheostomy Safety Project are effective, but resources are not available to educate the workforce at scale.

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Article Synopsis
  • Anti-Ro/SS-A antibodies are common in systemic autoimmune rheumatic diseases (SARDs) and suggest specific patient profiles; this study focused on the connection between protein biomarkers, symptom burden, and health-related quality of life (HR-QoL).
  • A pilot study enrolled anti-Ro positive SARD patients over six months, using various scales to measure HR-QoL and symptom burden, while assessing protein levels in the blood through advanced immunoassays.
  • Two patient clusters emerged: a 'low expression cluster' with greater symptom severity and poor HR-QoL, and a 'high expression cluster' tied to better physician assessments, highlighting potential protein markers that could lead to new therapeutic strategies for managing these patients.
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Objectives: This study investigated the relationships between the cochlear nerve (CN) health and sentence-level speech perception outcomes measured in quiet and noise in postlingually deafened adult cochlear implant (CI) users.

Design: Study participants included 24 postlingually deafened adult CI users with a Cochlear Nucleus device. For each participant, only one ear was tested.

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This paper introduces a systematic approach to the design of Direct Current-to-Digital Converter (DIDC) specifically engineered to overcome the limitations of traditional current measurement methodologies in System-on-Chip (SoC) designs. The proposed DIDC addresses critical challenges such as high power consumption, large area requirements, and the need for intermediate analog signals. By incorporating a current mirror in a cascode topology and managing the current across multiple binary-sized branches with the Successive Approximation Register (SAR) logic, the design achieves precise current measurement.

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Background: Acute otitis media with discharge (AOMd) results from a tympanic membrane perforation secondary to a middle ear infection. Currently, the impact of AOMd on children and young people (CYP) and their families is not well understood. There is also a need to explore the experience of healthcare professionals in treating AOMd.

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