Publications by authors named "I Iu Shmel'kov"

Aim: To examine etiological structure of fungal infections of the lower urinary tract (LUTI) in urological patients.

Material And Methods: The mycological screening of the urine in 52 patients (36 males and 16 females aged 21-83 years (mean age 63.6 years) was made by a E.

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A more than 80% incidence of herpes simplex virus, cytomegalovirus, and chlamydial infection was revealed in 58 patients with various gynecological diseases. In 50% cases the infection was mixed. An appreciable reduction of the gamma-interferon system was detected in 20 patients, which was caused by a concomitant infectious process, possibly provoking the development of the underlying disease.

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The data have been obtained which indicate that the effectiveness of vaccination with live trivalent poliomyelitis vaccine may be increased and 90--100% of the vaccinated infants under 1 year of age may develop marked resistance of the alimentary tract and high antibody titers in the blood serum to the threee types of poliomyelitis virus in the course of 3 vaccinations. Some regularities of the formation of immunity to individual poliomyelitis virus types in the course of 4 vaccinations with trivalent vaccine were revealed and specified. The results indicate that the contact of vaccine virus with the oropharyngeal tissues during immunization has a favourable effect on the development of immunity.

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It was shown that titers of the neutralizing activity of fecal extracts (coproantibody, CA) to poliomyelitis virus type II in the course of four administrations of live trivalent poliovaccine in drops directly into the mouth and in capsules were higher than CA titers to poliomyelitis virus types I and III. Particularly low CA titers to poliovirus types I and III were in children given the vaccine in the capsule, that is directly into the gastro-intestinal tract. Accordingly IgA levels in fecal extracts in this group of children were lower than in those given the vaccine in drops.

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