[Sensitivity of patients to immunomodulators in immunodeficiency diseases].

There were examined 198 patients, in whom immunodeficient (inflammatory, infectious and viral) diseases were revealed, as well as 10 healthy persons--for investigation of sensitivity of the blood neutrophils to immunomodulators (timalin, immunofan, polyoxidonium, timogen, erbisol). Most active one, in accordance to the investigation data, have evolved a synthetic preparation polyoxidonium, action mechanism of which is caused by direct activating impact on phagocytosis. Absence of sensitivity of the blood neutrophils towards activating stimuli (immunomodulators) in some patients was caused by a phenomenon, according to which the blood neutrophils, persisting durably in a preactivated state, further (while examining of the patients) have a reduced capacity for answering to stimulation.

[The administration of peflocine (pefloxacin) in the treatment and prevention of surgical infections].

The results of treatment of 23 patients with pefloxacin, administered because of the infectional complications in surgery development (1 group), and of 11 patients --for the infection development prophylaxis (2 group) were discussed. In the first group the recovery was noted in 83.3%, and significant improvement of condition--in 16.