Publications by authors named "I Itai Bendavid"
Article Synopsis
- Glycemic control during critical illness is crucial, with recommendations suggesting insulin therapy for glucose levels over 180 mg/dL, and possibly lowering it to 140 mg/dL for non-diabetics; this study explored the relationship between different glucose thresholds and 90-day mortality.
- A retrospective study analyzed data from 1,429 critical patients, revealing that diabetic individuals had higher mean glucose levels and mortality rates compared to non-diabetics.
- The findings indicated that non-diabetic patients with glucose levels exceeding 150 mg/dL were at a greater risk of mortality within 90 days, highlighting the importance of managing hyperglycemia in this group.
Article Synopsis
- Hypophosphatemia is a significant concern in critically ill patients receiving nutritional support, with over 59% of studied patients developing the condition.
- Factors such as age, BMI, pre-existing diabetes, and certain admission conditions were linked to a lower risk of developing hypophosphatemia, while trauma increased the risk.
- Interestingly, hypophosphatemia was found to be associated with a decreased risk of mortality, though factors like age and specific health scores remained critical indicators of ICU mortality.
Background: Current standard treatment for metastatic breast cancer (MBC) involves cyclin-dependent kinase 4/6 (CDK4/6) inhibitors with endocrine therapy, showing potential in enhancing anti-tumor immune responses.
Case Report: This report details a clinical case of MBC where palbociclib was co-administered with letrozole. The integration of allogeneic tumor vaccination to this treatment led to heightened interferon-γ production, expansion of CD8+ and NK cell populations, and positive delayed-type hypersensitivity reactions, indicating successful development of anti-tumor immunity.
Article Synopsis
- This study investigates how high flow nasal cannula (HFNC) oxygen therapy affects gastric reflux events and gastric residual volumes (GRV) in patients who were mechanically ventilated and then extubated.
- Using the smART+ Platform, researchers compared reflux events and GRV before and after patients switched to HFNC therapy.
- The results indicated that while GRV increased significantly on HFNC, the frequency of major reflux events showed no significant change between the two patient states.
Introduction: Persistent critical illness (PCI) is a syndrome in which the acute presenting problem has been stabilized, but the patient's clinical state does not allow ICU discharge. The burden associated with PCI is substantial. The most obvious marker of PCI is prolonged ICU length of stay (LOS), usually greater than 10 days.
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